Rheological Properties of Non-Adhesive Embolizing Compounds—The Key to Fine-Tuning Embolization Process-Modeling in Endovascular Surgery Full article
| Journal |
Polymers
ISSN: 2073-4360 |
||||
|---|---|---|---|---|---|
| Output data | Year: 2023, Volume: 15, Number: 4, Article number : 1060, Pages count : 18 DOI: 10.3390/polym15041060 | ||||
| Tags | embolic agent; rheology; hemodynamics; arteriovenous malformation (AVM); CFD | ||||
| Authors |
|
||||
| Affiliations |
|
Funding (3)
| 1 | Министерство науки и высшего образования Российской Федерации | FWGG-2021-0009 |
| 2 | Российский научный фонд | 20-71-10034 |
| 3 | Министерство науки и высшего образования Российской Федерации | 14.W03.31.0002 |
Abstract:
The study of polymers’ rheological properties is of paramount importance both for the problems of their industrial production as well as for their practical application. Two polymers used for embolization of arteriovenous malformations (AVMs) are studied in this work: Onyx-18r and
Squid-12r. Viscosity curve tests and computational fluid dynamics (CFD) were used to uncover viscosity law as a function of shear rate as well as behavior of the polymers in catheter or pathological tissue models. The property of thermal activation of viscosity was demonstrated, namely, the law of dependence of viscosity on temperature in the range from 20 ◦C to 37 ◦C was established. A zone of viscosity nonmonotonicity was identified, and a physical interpretation of the dependence of the embolic polymers’ viscosity on the shear rate was given on the basis of Cisco’s model. The obtained
empirical constants will be useful for researchers based on the CFD of AVMs. A description of the
process of temperature activation of the embolic polymers’ viscosity is important for understanding
the mechanics of the embolization process by practicing surgeons as well as for producing new
prospective embolic agent
Cite:
Kuyanova I.
, Chupakhin A.
, Besov A.
, Gorbatykh A.
, Kislitsin D.
, Orlov K.
, Parshin D.
Rheological Properties of Non-Adhesive Embolizing Compounds—The Key to Fine-Tuning Embolization Process-Modeling in Endovascular Surgery
Polymers. 2023. V.15. N4. 1060 :1-18. DOI: 10.3390/polym15041060 WOS Scopus РИНЦ OpenAlex
Rheological Properties of Non-Adhesive Embolizing Compounds—The Key to Fine-Tuning Embolization Process-Modeling in Endovascular Surgery
Polymers. 2023. V.15. N4. 1060 :1-18. DOI: 10.3390/polym15041060 WOS Scopus РИНЦ OpenAlex
Identifiers:
| Web of science: | WOS:000942505700001 |
| Scopus: | 2-s2.0-85149035255 |
| Elibrary: | 50459012 |
| OpenAlex: | W4321459628 |