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Rheological Properties of Non-Adhesive Embolizing Compounds—The Key to Fine-Tuning Embolization Process-Modeling in Endovascular Surgery Научная публикация

Журнал Polymers
ISSN: 2073-4360
Вых. Данные Год: 2023, Том: 15, Номер: 4, Номер статьи : 1060, Страниц : 18 DOI: 10.3390/polym15041060
Ключевые слова embolic agent; rheology; hemodynamics; arteriovenous malformation (AVM); CFD
Авторы Kuyanova Iuliia 1 , Chupakhin Alexander 1 , Besov Alexey 1 , Gorbatykh Anton 2 , Kislitsin Dmitry 2 , Orlov Kirill 2 , Parshin Daniil 1
Организации
1 Lavrentyev Institute of Hydrodynamics SB RAS, 630090 Novosibirsk, Russia
2 Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia

Информация о финансировании (3)

1 Министерство науки и высшего образования Российской Федерации FWGG-2021-0009
2 Российский научный фонд 20-71-10034
3 Министерство науки и высшего образования Российской Федерации 14.W03.31.0002

Реферат: The study of polymers’ rheological properties is of paramount importance both for the problems of their industrial production as well as for their practical application. Two polymers used for embolization of arteriovenous malformations (AVMs) are studied in this work: Onyx-18r and Squid-12r. Viscosity curve tests and computational fluid dynamics (CFD) were used to uncover viscosity law as a function of shear rate as well as behavior of the polymers in catheter or pathological tissue models. The property of thermal activation of viscosity was demonstrated, namely, the law of dependence of viscosity on temperature in the range from 20 ◦C to 37 ◦C was established. A zone of viscosity nonmonotonicity was identified, and a physical interpretation of the dependence of the embolic polymers’ viscosity on the shear rate was given on the basis of Cisco’s model. The obtained empirical constants will be useful for researchers based on the CFD of AVMs. A description of the process of temperature activation of the embolic polymers’ viscosity is important for understanding the mechanics of the embolization process by practicing surgeons as well as for producing new prospective embolic agent
Библиографическая ссылка: Kuyanova I. , Chupakhin A. , Besov A. , Gorbatykh A. , Kislitsin D. , Orlov K. , Parshin D.
Rheological Properties of Non-Adhesive Embolizing Compounds—The Key to Fine-Tuning Embolization Process-Modeling in Endovascular Surgery
Polymers. 2023. V.15. N4. 1060 :1-18. DOI: 10.3390/polym15041060 WOS Scopus РИНЦ OpenAlex
Идентификаторы БД:
Web of science: WOS:000942505700001
Scopus: 2-s2.0-85149035255
РИНЦ: 50459012
OpenAlex: W4321459628
Цитирование в БД:
БД Цитирований
OpenAlex 4
РИНЦ 5
Scopus 3
Web of science 5
Альметрики: