Incidence and risk factors of venous thromboembolic events after resection of various brain tumors

Incidence and risk factors of venous thromboembolic events after resection of various brain tumors Full article

Journal

Zhurnal Voprosy Nejrokhirurgii Imeni N.N. Burdenko
ISSN: 0042-8817

Output data

Year: 2021, Volume: 85, Number: 3, Pages: 63-77 Pages count : 15 DOI: 10.17116/neiro20218503163

Tags

Complication; DVT; Pulmonary embolism; Thromboembolism; Thrombosis; Tumor

Authors

Bervitskiy A.V. ^1,2,3 , Moisak G.I. ^1,4 , Guzhin V.E. ¹ , Amelina E.V. ⁴ , Kalinovskiy A.V. ¹ , Rzaev D.A. ^1,4

Affiliations

1	FSBI «Federal Center for Neurosurgery» of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation
2	Research Institute of Clinical and Experimental Lymphology - Branch of the Institute of Cytology and Genetics SB RAS, Novosibirsk, Russian Federation
3	Institute of Hydrodynamics. M.A. Lavrent’ev SB RAS, Novosibirsk, Russian Federation
4	Novosibirsk State University, Novosibirsk, Russian Federation

Venous thromboembolic events (VTE) can significantly complicate postoperative period in neurosurgical patients. It is known that patients with brain tumors are especially susceptible to VTE. Objective. To determine the incidence and risk factors of VTE in patients with various brain tumors. Material and methods. All patients with brain tumors underwent surgery in 2019 (n=610). They were divided into the groups depending on tumor type: sellar region, intracerebral, extracerebral neoplasms and metastases. All patients underwent screening and prevention of VTE in accordance with the protocol accepted in the hospital. We analyzed the incidence of VTE in each group and significance of various risk factors. Results. Overall incidence of VTE was 14.9% (91 cases). Deep vein thrombosis (DVT) was the most common - 85 cases (93.4%). Less common events were DVT combined with pulmonary embolism (PE) (n=5, 5.5%) and PE alone (n=1; 1.1%). PE caused death in 2 cases (0.3%). In patients with sellar tumors, incidence was 21.7% [13.4%; 29.35%], among intracerebral tumors - 13.8% [9.04%; 18.62%], extracerebral neoplasms - 15.4% [11.02%; 19.69%], metastases - 7.9% [1.32%; 11.84%]. Univariate and multivariate analysis revealed some risk factors of VTEs such as gender, age, surgery time, length of ICU-stay over 12 hours, body mass index >30 kg/m2. Moreover, risk factors have different significance in patients with different types of tumors. Conclusion. In this study, we found a high incidence of VTE among patients with brain tumors. Incidence and risk factors of VTE depend on the type of tumor. © A.V. BERVITSKIY, G.I. MOISAK, V.E. GUZHIN, E.V. AMELINA, A.V. KALINOVSKIY, D.A. RZAEV.

Bervitskiy A.V. , Moisak G.I. , Guzhin V.E. , Amelina E.V. , Kalinovskiy A.V. , Rzaev D.A.
Incidence and risk factors of venous thromboembolic events after resection of various brain tumors
Zhurnal Voprosy Nejrokhirurgii Imeni N.N. Burdenko. 2021. V.85. N3. P.63-77. DOI: 10.17116/neiro20218503163 Scopus OpenAlex

Бервицкий А.В. , Мойсак Г.И. , Гужин В.Э. , Амелина (Морозова) Е.В. , Калиновский А.В. , Рзаев Д.А.
ЧАСТОТА И ФАКТОРЫ РИСКА РАЗВИТИЯ ВЕНОЗНЫХ ТРОМБОЭМБОЛИЧЕСКИХ ОСЛОЖНЕНИЙ У ПАЦИЕНТОВ ПОСЛЕ УДАЛЕНИЯ РАЗЛИЧНЫХ ВИДОВ ОПУХОЛЕЙ ГОЛОВНОГО МОЗГА
«Вопросы нейрохирургии» имени Н.Н. Бурденко. 2021. Т.85. №3. С.63-75. РИНЦ

Scopus:	2-s2.0-85109059062
OpenAlex:	W3176913110

DB	Citing
Scopus	4
OpenAlex	2