Abstract: Numerical modeling is an effective tool for preoperative planning. The present work is devoted to a retrospective analysis of neurosurgical treatments for the occlusion of cerebral aneurysms using flow-diverters and hemodynamic factors affecting stent endothelization. Several different geometric approaches have been considered for virtual flow-diverters deployment. A comparative analysis of hemodynamic parameters as a result of computational modeling has been carried out basing on the four clinical cases: one successful treatment, one with no occlusion and two with in stent stenosis. For the first time, a quantitative assessment of both: the limiting magnitude of shear stresses that are necessary for the occurrence of in stent stenosis (MaxWSS > 1.23) and for conditions in which endothelialization is insufficiently active and occlusion of the cervical part of the aneurysm does not occur (MaxWSS < 1.68)—has been statistacally proven (p < 0.01).

Cite: Tikhvinskii D. , Kuianova J. , Kislitsin D. , Orlov K. , Gorbatykh A. , Parshin D.
Numerical Assessment of the Risk of Abnormal Endothelialization for Diverter Devices: Clinical Data Driven Numerical Study
Journal of Personalized Medicine. 2022. V.12. N4. 652 :1-25. DOI: 10.3390/jpm12040652 WOS Scopus РИНЦ OpenAlex

Identifiers:

Web of science:	WOS:000786242000001
Scopus:	2-s2.0-85129141480
Elibrary:	48581136
OpenAlex:	W4224253620

Citing:

DB	Citing
Scopus	3
OpenAlex	5
Elibrary	5
Web of science	2

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