Effect of type 1 diabetes mellitus of different duration on the Willis’ circle angioarchitectonics

Effect of type 1 diabetes mellitus of different duration on the Willis’ circle angioarchitectonics Full article

Conference

19th International Conference on the Methods of Aerophysical Research
13-19 Aug 2018 , Новосибирск

Journal

AIP Conference Proceedings
ISSN: 0094-243X

Output data

Year: 2018, Article number : 040088, Pages count : 5 DOI: 10.1063/1.5065362

Authors

Yankova G.S. ^1,2 , Tur D.A. ³ , Parshin D.V. ^1,2 , Cherevko A.A. ^1,2 , Akulov A.E. ^1,3

Affiliations

1	Novosibirsk State University
2	Lavrentyev Institute of Hydrodynamics of the Siberian Branch of the Russian Academy of Sciences
3	Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences

The vascular system of the brain has a complex structure. One of the most important of its parts is the Willis’ circle. In the article, we consider the effect of type 1 diabetes mellitus duration 1 and 2 months on the angiarchitectonics of the Willis’ circle of NODSCID mice. MRA data was supplemented with mathematical post-processing. On the basis of the 3D images of blood vessels of the brain, their geometrical characteristics — angles of the vessels and the area of their orthogonal cross-sections were measured. Based on the data obtained, the following conclusions can be made: for animals with a disease development period of 1 month, there are no significant differences in the architectonics of the Willis’ circle. However, with the duration of the disease for 2 months, diabetes begins to affect the architectonics of major vessels of the brain.

Yankova G.S. , Tur D.A. , Parshin D.V. , Cherevko A.A. , Akulov A.E.
Effect of type 1 diabetes mellitus of different duration on the Willis’ circle angioarchitectonics
AIP Conference Proceedings. 2018. 040088 :1-5. DOI: 10.1063/1.5065362 Scopus РИНЦ OpenAlex

Scopus:	2-s2.0-85056329181
Elibrary:	38622924
OpenAlex:	W2899129470

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